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    ZONISEP uses: This medication is used with other medications to control certain types of seizure problems (e.g., partial seizures). This medication is usually used when other medications have not been effective in controlling your seizures. Controlling seizures helps to prevent injury from falling and allows you to lead a more normal life. Zonisamide belongs to a class of drugs known as anticonvulsants. It works by controlling the abnormal electrical activity in the brain that occurs during a seizure.How to use Zonisamide OralTake this medication by mouth with or without food, usually 1-2 times daily or as directed by your doctor. Take with food or milk if stomach upset occurs. Your doctor will start you on a smaller dose once daily, increasing it every 2 weeks until you are taking the full dose. Swallow the capsules whole. Do not crush or chew the capsules.Dosage is based on your age, medical condition, blood levels of zonisamide, and response to therapy. It may take several weeks to months until your doctor determines the correct dose for controlling your seizures.This medication works best when the amount of drug in your body is kept at a constant level. Therefore, take this drug at evenly spaced intervals. To help you remember, take it at the same time(s) each day.It is very important to continue taking this medication (and other anticonvulsant medications) exactly as prescribed by your doctor. Do not take more or less of this drug than prescribed or stop taking it (or other anticonvulsant medicines) even for a short time unless directed to do so by your doctor. Skipping or changing your dose without approval from your doctor may cause seizure control to worsen, cause a very severe seizure that is difficult to treat (status epilepticus), or worsen side effects.

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